Dr. Rowe’s clinical interests and research are focused on medical conditions characterized by chronic fatigue. His work first described an association between treatable circulatory disorders and chronic fatigue syndrome (CFS), and has also brought to light several novel contributors to fatigue. These include connective tissue laxity and Ehlers-Danlos syndrome as risk factors for both orthostatic intolerance and CFS, the importance of milk protein intolerance as a contributor to symptoms in adolescents and young adults with CFS, and abnormal range of motion in soft tissues and nerves as a biomechanical contributor to CFS symptoms. His research has been funded by the National Institutes of Health, the US Department of Defense, the Solve ME/CFS Initiative, and several smaller foundations, as well as by private philanthropy. He has directed the Chronic Fatigue Clinic at the Children’s Center since 1996, where he is the inaugural recipient of the Sunshine Natural Wellbeing Foundation Chair in Chronic Fatigue and Related Disorders.